The Yukon Denali seats up to 7 passengers with its standard three rows of seats. It comes equipped with a three-passenger split bench second row and a 60/40 split-folding third row bench.

The Yukon Denali utilizes a traditional body-on-frame construction providing rugged truck underpinnings compared to car-based crossover rivals.

GMC offers both single-speed AWD and two-speed 4WD with low range for increased off-road prowess. 4WD models have greater capability in sand, mud, and deep snow.